Direct interactions between rab GTPases and cargo

被引：29

作者：

Smythe, E ^{[1
]}

机构：

[1] Univ Dundee, Wellcome Trust Bioctr, Div Cell Biol & Immunol, Sch Life Sci, Dundee DD1 5EH, Scotland

来源：

MOLECULAR CELL | 2002年 / 9卷 / 02期

关键词：

D O I：

10.1016/S1097-2765(02)00462-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rab family of small GTPases has numerous roles in intracellular transport including budding, tethering, and fusion of vesicles as well as organelle motility. New data show that cargo proteins are also rab effectors and can therefore regulate their own trafficking by direct interactions with the transport machinery.

引用

页码：205 / 206

页数：2

共 9 条

[1] Role of Rab9 GTPase in facilitating receptor recruitment by TIP47 [J].

Carroll, KS ;

Hanna, J ;

Simon, I ;

Krise, J ;

Barbero, P ;

Pfeffer, SR .

SCIENCE, 2001, 292 (5520) :1373-1376

[2] Multiple aspects of Rab protein action in the secretory pathway: Focus on Rab3 and Rab6 [J].

Darchen, F ;

Goud, B .

BIOCHIMIE, 2000, 82 (04) :375-384

[3] The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion [J].

Geppert, M ;

Goda, Y ;

Stevens, CF ;

Sudhof, TC .

NATURE, 1997, 387 (6635) :810-814

[4] A novel role for Rab5-GDI in ligand sequestration into calthrin-coated pits [J].

McLauchlan, H ;

Newell, J ;

Morrice, N ;

Osborne, A ;

West, M ;

Smythe, E .

CURRENT BIOLOGY, 1998, 8 (01) :34-45

[5] Regulation of protein traffic in polarized epithelial cells: The polymeric immunoglobulin receptor model [J].

Mostov, KE ;

Altschuler, Y ;

Chapin, SJ ;

Enrich, C ;

Low, SH ;

Luton, F ;

RichmanEisenstat, J ;

Singer, KL ;

Tang, K ;

Weimbs, T .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1995, 60 :775-781

[6] Rab5 association with the angiotensin II type 1A receptor promotes Rab5 GTP binding and vesicular fusion [J].

Seachrist, JL ;

Laporte, SA ;

Dale, LB ;

Babwah, AV ;

Caron, MG ;

Anborgh, PH ;

Ferguson, SSG .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (01) :679-685

[7] Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5 and Rab11 [J].

Sönnichsen, B ;

De Renzis, S ;

Nielsen, E ;

Rietdorf, J ;

Zerial, M .

JOURNAL OF CELL BIOLOGY, 2000, 149 (04) :901-913

[8] Direct interaction between rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells [J].

van IJzendoorn, SCD ;

Tuvim, MJ ;

Weimbs, T ;

Dickey, BF ;

Mostov, KE .

DEVELOPMENTAL CELL, 2002, 2 (02) :219-228

[9] Rab proteins as membrane organizers [J].

Zerial, M ;

McBride, H .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (02) :107-117

← 1 →