Mild reduction of carboxylic acids to alcohols using cyanuric chloride and sodium borohydride

被引：112

作者：

Falorni, M ^{[1
]}

Porcheddu, A ^{[1
]}

Taddei, M ^{[1
]}

机构：

[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 23期

关键词：

reduction; carboxylic acids; alcohols; amino acids;

D O I：

10.1016/S0040-4039(99)00734-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several carboxylic acids, including N-Boc, N-Cbz and N-Fmoc amino acids were reduced to the corresponding alcohols by activation of the carboxy function with cyanuric chloride and N-methylmorpholine followed by reduction with aqueous sodium borohydride. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4395 / 4396

页数：2

共 7 条

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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (11) : 3078 - 3085
[7] [No title captured]

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