Blink reflex in migraine and tension-type headache

被引：30

作者：

Avramidis, TG ^{[1
]}

Podikoglou, DG ^{[1
]}

Anastasopoulos, IE ^{[1
]}

Koutroumanidis, MA ^{[1
]}

Papadimitriou, AL ^{[1
]}

机构：

[1] Red Cross Hosp, Dept Neurol, Athens, Greece

来源：

HEADACHE | 1998年 / 38卷 / 09期

关键词：

migraine; tension-type headache; blink reflex;

D O I：

10.1046/j.1526-4610.1998.3809691.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The blink reflex was studied in 19 patients with migraine, 10 patients with tension-type headache, and 30 healthy controls. Significantly lower values of R-2 and R-2' amplitude and size were found in the migraine group, compared with the healthy control group. The differences were independent of the stimulation side (headache or nonheadache) and highly significant (P<0.001). The abnormalities of R-2 and R-2' amplitude and size were found only during the headache phase of migraine, being normal between migraine attacks. R-1 latency and amplitude were normal in all patients. The blink reflex was normal in all the patients with tension-type headache. Subcutaneous injection of sumatriptan in 10 of the 19 migraineurs, during the headache phase, restored R-2 and R-2' amplitude and size values to normal. Our findings indicate that the brain stem interneuron part of the blink reflex are may be diffusely suppressed in migraine, only during the headache phase. Furthermore, blink reflex may be an objective laboratory method to monitor the effectiveness of specific drugs proposed for the treatment of migraine.

引用

页码：691 / 696

页数：6

共 15 条

[11] EXTEROCEPTIVE SUPPRESSION OF TEMPORALIS MUSCLE-ACTIVITY IN CHRONIC HEADACHE [J].