Synthesis and absolute stereochemistry of thysanone

被引：36

作者：

Donner, CD ^{[1
]}

Gill, M ^{[1
]}

机构：

[1] Univ Melbourne, Sch Chem, Parkville, Vic 3052, Australia

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 20期

基金：

澳大利亚研究理事会;

关键词：

thysanone; HRV 3C-protease inhibitor; synthesis; absolute stereochemistry;

D O I：

10.1016/S0040-4039(99)00570-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure and absolute stereochemistry of thysanone 3, a fungal benzoisochromanquinone with potent human rhinovirus 3C-protease inhibitory activity, is established by the total synthesis of its antipode 1 from (S)-propylene oxide. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3921 / 3924

页数：4