Combinatorial solid-phase synthesis using D-Galactose as a chiral five-dimension-diversity scaffold

被引：55

作者：

Kallus, C

Opatz, T

Wunberg, T

Schmidt, W

Henke, S

Kunz, H ^{[1
]}

机构：

[1] Univ Mainz, Inst Organ Chem, D-55099 Mainz, Germany

[2] Hoechst Marion Roussel Deutschland GMBH, D-65926 Frankfurt, Germany

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 44期

关键词：

combinatorial chemistry; carbohydrates; protecting groups; solid-phase synthesis;

D O I：

10.1016/S0040-4039(99)01690-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

All five hydroxy groups of galactose as the scaffold are used for selective coupling of side chains in a combinatorial methodology by application of a set of orthogonally stable protecting groups in combination with a thioglycoside anchor. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：7783 / 7786

页数：4

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