Isolation and characterization of the mouse (Mus musculus) somatostatin receptor type-4-encoding gene (mSSTR4)

被引：24

作者：

Schwabe, W ^{[1
]}

Brennan, MB ^{[1
]}

Hochgeschwender, U ^{[1
]}

机构：

[1] NIMH,NSB,MOLEC GENET UNIT,BETHESDA,MD 20892

来源：

GENE | 1996年 / 168卷 / 02期

关键词：

gene cloning; oligodeoxynucleotide hybridization; nucleotide sequence; expression; RT-PCR;

D O I：

10.1016/0378-1119(95)00748-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have isolated and sequenced the mouse somatostatin receptor subtype-4-encoding gene (mSSTR4). The mSSTR4 gene encodes 384 amino acids (aa). The deduced mouse SSTR4 has 95 and 89% aa identity with the deduced rat and human SSTR4, respectively, while it has lower aa identity with the other mouse subtypes (mSSTR1, 60%; mSSTR2, 47%; mSSTR3, 42%). Using an RT-PCR technique, we show that the mSSTR4 gene is expressed in brain, but not in liver, heart, spleen or kidney of the adult mouse.

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页码：233 / 235

页数：3

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