Modeling malignant melanoma in mice: pathogenesis and maintenance

被引:12
作者
Chin, L
机构
[1] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Dept Adult Oncol, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
melanoma; RAS; tumor maintenance; mouse model;
D O I
10.1038/sj.onc.1203106
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:5304 / 5310
页数:7
相关论文
共 65 条
[41]   Oncogenes as inducers of tumor angiogenesis [J].
Rak, J ;
Filmus, J ;
Finkenzeller, G ;
Grugel, S ;
Marme, D ;
Kerbel, RS .
CANCER AND METASTASIS REVIEWS, 1995, 14 (04) :263-277
[42]   Lifetime risk for development of skin cancer in the US population: Current estimate is now 1 in 5 [J].
Rigel, DS ;
Friedman, RJ ;
Kopf, AW .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1996, 35 (06) :1012-1013
[43]   The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53 [J].
Robertson, KD ;
Jones, PA .
MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (11) :6457-6473
[44]   GROWTH-FACTORS IN MELANOMA [J].
RODECK, U ;
HERLYN, M .
CANCER AND METASTASIS REVIEWS, 1991, 10 (02) :89-101
[45]   The p16INK4a/CDKN2A tumor suppressor and its relatives [J].
Ruas, M ;
Peters, G .
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1998, 1378 (02) :F115-F177
[46]  
SAENZSANTAMARIA M, 1995, AM J DERMATOPATH, V17, P344
[47]   Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a) [J].
Serrano, M ;
Lin, AW ;
McCurrach, ME ;
Beach, D ;
Lowe, SW .
CELL, 1997, 88 (05) :593-602
[48]   Role of the INK4a locus in tumor suppression and cell mortality [J].
Serrano, M ;
Lee, HW ;
Chin, L ;
CordonCardo, C ;
Beach, D ;
DePinho, RA .
CELL, 1996, 85 (01) :27-37
[49]   The INK4A/ARF locus and its two gene products [J].
Sharpless, NE ;
DePinho, RA .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 1999, 9 (01) :22-30
[50]   CDK inhibitors:: positive and negative regulators of G1-phase progression [J].
Sherr, CJ ;
Roberts, JM .
GENES & DEVELOPMENT, 1999, 13 (12) :1501-1512