Molecular genetics of the fibrinolytic and coagulation systems in haemostasis, thrombogenesis, restenosis and atherosclerosis

被引:33
作者
Carmeliet, P
Collen, D
机构
[1] Ctr. Transgene Technol. Gene Ther., Flanders Interuniv. Inst. Biotech., Leuven
[2] Ctr. Transgene Technol. Gene Ther., Flanders Interuniv. Inst. Biotech., University of Leuven, B-3000 Leuven
关键词
PLASMINOGEN-ACTIVATOR; DEFICIENT MICE; HOMOLOGOUS RECOMBINATION; TISSUE FACTOR; THROMBOLYSIS; EXPRESSION; DISRUPTION; THROMBOSIS; UROKINASE; CELLS;
D O I
10.1097/00041433-199704000-00010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The plasminogen and coagulation systems have been extensively characterized at the biochemical level. Recent gene targeting and gene transfer studies have provided novel insights into their role in the formation of blood vessels and in the pathogenesis of blood vessel disorders including thrombosis, restenosis and atherosclerosis.
引用
收藏
页码:118 / 125
页数:8
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