Marker2sequence, mine your QTL regions for candidate genes

被引：8

作者：

Chibon, Pierre-Yves ^{[1
,2
,3
]}

Schoof, Heiko ^{[4
]}

Visser, Richard G. F. ^{[1
,3
]}

Finkers, Richard ^{[1
,3
]}

机构：

[1] Univ Wageningen & Res Ctr, Wageningen UR Plant Breeding, NL-6700 AJ Wageningen, Netherlands

[2] Grad Sch Expt Plant Sci, NL-6700 AA Wageningen, Netherlands

[3] Ctr Biosyst Genom, NL-6700 AA Wageningen, Netherlands

[4] Univ Bonn, INRES, D-53115 Bonn, Germany

来源：

BIOINFORMATICS | 2012年 / 28卷 / 14期

关键词：

WEB;

D O I：

10.1093/bioinformatics/bts298

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Marker2sequence (M2S) aims at mining quantitative trait loci (QTLs) for candidate genes. For each gene, within the QTL region, M2S uses data integration technology to integrate putative gene function with associated gene ontology terms, proteins, pathways and literature. As a typical QTL region easily contains several hundreds of genes, this gene list can then be further filtered using a keyword-based query on the aggregated annotations. M2S will help breeders to identify potential candidate genes for their traits of interest.

引用

页码：1921 / 1922

页数：2

共 14 条

[1] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[2] The Semantic Web - A new form of Web content that is meaningful to computers will unleash a revolution of new possibilities [J].

Berners-Lee, T ;

Hendler, J ;

Lassila, O .

SCIENTIFIC AMERICAN, 2001, 284 (05) :34-+

[3]

Carroll JJ., 2004, P 13 INT WORLD WID W, P74, DOI [10.1145/1013367.1013381, DOI 10.1145/1013367.1013381]

[4]

Erling O., 2007, CSSW, P59

[5] Identification, analysis, and utilization of conserved ortholog set markers for comparative genomics in higher plants [J].

Fulton, TM ;

Van der Hoeven, R ;

Eannetta, NT ;

Tanksley, SD .

PLANT CELL, 2002, 14 (07) :1457-1467

[6] Infrastructure for the life sciences: design and implementation of the UniProt website [J].

Jain, Eric ;

Bairoch, Amos ;

Duvaud, Severine ;

Phan, Isabelle ;

Redaschi, Nicole ;

Suzek, Baris E. ;

Martin, Maria J. ;

McGarvey, Peter ;

Gasteiger, Elisabeth .

BMC BIOINFORMATICS, 2009, 10

[7] Protein function prediction and annotation in an integrated environment powered by web services (AFAWE) [J].

Joecker, Anika ;

Hoffmann, Fabian ;

Groscurth, Andreas ;

Schoof, Heiko .

BIOINFORMATICS, 2008, 24 (20) :2393-2394

[8]

LINCOLN RE, 1950, GENETICS, V35, P206

[9]

Nicole R., 2009, Nat. Prec, DOI DOI 10.1038/NPRE.2009.3193.1

[10] RECOMBINANT INBRED LINES FOR GENETIC-MAPPING IN TOMATO [J].

PARAN, I ;

GOLDMAN, I ;

TANKSLEY, SD ;

ZAMIR, D .

THEORETICAL AND APPLIED GENETICS, 1995, 90 (3-4) :542-548

← 1 2 →