Cytokines as a key component of cancer-related inflammation

被引：278

作者：

Germano, Giovanni ^{[1
]}

Allavena, Paola ^{[1
]}

Mantovani, Alberto ^{[1
,2
,3
]}

机构：

[1] Ist Clin Humanitas IRCCS, I-20089 Milan, Italy

[2] Fdn Humanitas Ric, I-20089 Milan, Italy

[3] Univ Milan, Inst Gen Pathol, Milan, Italy

来源：

CYTOKINE | 2008年 / 43卷 / 03期

关键词：

Cancer-related; Inflammation; Tumor-associated macrophages; Cytokines; Chemokines;

D O I：

10.1016/j.cyto.2008.07.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inflammatory conditions in some tissues increase the risk of cancer. Cytokines and chemokines are components of an intensive dialog promoting angiogenesis, metastasis, subversion of adaptive immunity and changing response to hormones and to chemotherapeutic agents. Cytokines involved in cancer-related inflammation represent a target for innovative diagnostic and therapeutic strategies, and a future challenge for scientists and clinicians. (C) 2008 Elsevier Ltd. All rights reserved.

引用

收藏

页码：374 / 379

页数：6

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