Recombinant baculoviruses as expression vectors for insect and mammalian cells

被引：105

作者：

Kost, TA ^{[1
]}

Condreay, JP ^{[1
]}

机构：

[1] Glaxo Wellcome Inc, Dept Mol Sci, Res Triangle Pk, NC 27709 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1999年 / 10卷 / 05期

关键词：

D O I：

10.1016/S0958-1669(99)00005-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Baculovirus expression vectors are widely used for expressing heterologous proteins in cultured insect cells. Recent advances include further development of the system for production of multi-subunit protein complexes, cc-expression of protein-modifying enzymes to improve heterologous protein production, and additional applications of baculovirus display technology. The application of modified baculovirus vectors for gene expression in mammalian cells continues to expand.

引用

页码：428 / 433

页数：6

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