Separation of tanshinones from Salvia miltiorrhiza Bunge by multidimensional counter-current chromatography

被引：57

作者：

Tian, G

Zhang, TY

Zhang, YB

Ito, Y

机构：

[1] NIH, NHLBI, Biophys Chem Lab, Bethesda, MD 20892 USA

[2] Beijing Inst New Technol Applicat, Beijing 100035, Peoples R China

来源：

JOURNAL OF CHROMATOGRAPHY A | 2002年 / 945卷 / 1-2期

关键词：

Salvia miltiorrhiza; counter-current chromatography; plant materials; preparative chromatography; tanshinones;

D O I：

10.1016/S0021-9673(01)01495-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Analytical and preparative high-speed counter-current chromatography (HSCCC) was successfully used for the isolation and purification of tanshinones from the roots of Salvia miltiorrhiza Bunge. Using multidimensional HSCCC, four major components including tanshinone IIA (16 mg), tanshinone I (10 mg), dihydrotanshinone I (7 mg) and cryptotanshinone (II mg) were isolated each at high purity of over 95%. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：281 / 285

页数：5

共 8 条

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[2]

ITO Y, 1986, CRIT REV ANAL CHEM, V17, P65, DOI 10.1080/10408348608542792

[3] STUDIES ON CARDIOVASCULAR ACTIONS OF SALVIA-MILTIORRHIZA [J].