The prevalence of Parkinson's disease in rural Tanzania

被引：82

作者：

Dotchin, Catherine ^{[1
]}

Msuya, Olivia ^{[2
]}

Kissima, John ^{[3
]}

Massawe, John ^{[3
]}

Mhina, Ali ^{[3
]}

Moshy, Addess ^{[3
]}

Aris, Eric ^{[4
]}

Jusabani, Ahmed ^{[2
]}

Whiting, David ^{[5
]}

Masuki, Gabriel ^{[3
]}

Walker, Richard ^{[1
]}

机构：

[1] N Tyneside Dist Gen Hosp, N Shields NE29 0NH, Tyne & Wear, England

[2] Kilimanjaro Christian Med Ctr, Moshi, Tanzania

[3] Hai Dist Med Off, Adult Morbid & Mortal Project, Bomangombe, Hai, Tanzania

[4] Muhimbili Hosp, Dar Es Salaam, Tanzania

[5] Newcastle Univ, Sch Med, Inst Hlth & Soc, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

MOVEMENT DISORDERS | 2008年 / 23卷 / 11期

关键词：

Parkinson's disease; prevalence; sub-Saharan Africa;

D O I：

10.1002/mds.21898

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The prevalence of Parkinson's disease (PD) varies worldwide front 7 to 450 per 100,000, and appears low ill sub-Saharan Africa (SSA) but few data exist. We conducted a prevalence Study of PD in rural Tanzania. A door-to-door study Was conducted in the Hai district project area (population 161,071). Using a screening questionnaire followed by structured history and examination of positive responders. Diagnosis was based oil the UK PD Society Brain Bank Criteria. 33 (23 men) cases of ID were detected. with mean age 74 years (range 38-94). One patient died before the prevalence date. 79% were previously undiagnosed and untreated. Mean duration of symptoms was 5 years, and median Hoehn and Yahr stage 3. Crude prevalence rates were 30/100,000 (men), 11/100,000 (women) and 20/100,000 (combined). The direct age-standardized prevalence rates compared with the UK population were 64/100,000 (men) 20/100,000 (women) and 40/100,000 (combined). These rates are higher than previously reported from SSA, but still lower than the developed world. Many PD patients in SSA may never be diagnosed or treated, with consequent reduction in their life expectancy and quality of life. With the world population ageing PD is predicted to become an increasing problem. (C) 2007 Movement Disorder Society.

引用

页码：1567 / 1572

页数：6

共 29 条

[11] Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study [J].

Murray, CJL ;

Lopez, AD .

LANCET, 1997, 349 (9063) :1436-1442

[12] A SCREENING AND ALERTING QUESTIONNAIRE FOR PARKINSONISM [J].

MUTCH, WJ ;

SMITH, WC ;

SCOTT, RF .

NEUROEPIDEMIOLOGY, 1991, 10 (03) :150-156

[13] Parkinson's disease in Africa: A systematic review of epidemiologic and genetic studies [J].

Okubadejo, Njideka U. ;

Bower, James H. ;

Rocca, Walter A. ;

Maraganore, Demetrius M. .

MOVEMENT DISORDERS, 2006, 21 (12) :2150-2156

[14] NEUROLOGICAL DISORDERS IN NIGERIAN AFRICANS - A COMMUNITY-BASED STUDY [J].

OSUNTOKUN, BO ;

ADEUJA, AOG ;

SCHOENBERG, BS ;

BADEMOSI, O ;

NOTTIDGE, VA ;

OLUMIDE, AO ;

IGE, O ;

YARIA, F ;

BOLIS, CL .

ACTA NEUROLOGICA SCANDINAVICA, 1987, 75 (01) :13-21

[15] The prevalence of Parkinson's disease in an area of North Tyneside in the North-East of England [J].

Porter, B ;

Macfarlane, R ;

Unwin, N ;

Walker, R .

NEUROEPIDEMIOLOGY, 2006, 26 (03) :156-161

[16]

Racette BA, 2004, MOVEMENT DISORD, V19, pS186

[17] COMPARISON OF THE PREVALENCE OF PARKINSONS-DISEASE IN BLACK POPULATIONS IN THE RURAL UNITED-STATES AND IN RURAL NIGERIA - DOOR-TO-DOOR COMMUNITY STUDIES [J].

SCHOENBERG, BS ;

OSUNTOKUN, BO ;

ADEUJA, AOG ;

BADEMOSI, O ;

NOTTIDGE, V ;

ANDERSON, DW ;

HAERER, AF .

NEUROLOGY, 1988, 38 (04) :645-646

[18] Cross sectional prevalence survey of idiopathic Parkinson's disease and parkinsonism in London [J].

Schrag, A ;

Ben-Shlomo, Y ;

Quinn, NP .

BRITISH MEDICAL JOURNAL, 2000, 321 (7252) :21-+

[19] DATATOP - A MULTICENTER CONTROLLED CLINICAL-TRIAL IN EARLY PARKINSONS-DISEASE [J].

SHOULSON, I .

ARCHIVES OF NEUROLOGY, 1989, 46 (10) :1052-1060

[20]

TANNER C, 1999, ANN NEUROL, V28, P267

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