Hydrodynamically Driven Self-Assembly of Giant Vesicles of Metal Nanoparticles for Remote-Controlled Release

被引:125
作者
He, Jie [1 ]
Wei, Zengjiang [1 ,2 ]
Wang, Lei [1 ,3 ]
Tomova, Zuleykhan [1 ]
Babu, Taarika [1 ]
Wang, Chaoyang [2 ]
Han, Xiaojun [3 ]
Fourkas, John T. [1 ,4 ]
Nie, Zhihong [1 ]
机构
[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA
[2] S China Univ Technol, Res Inst Mat Sci, Guangzhou 510640, Guangdong, Peoples R China
[3] Harbin Inst Technol, Sch Chem Engn & Technol, Harbin 150001, Peoples R China
[4] Univ Maryland, Inst Phys Sci & Technol, College Pk, MD 20742 USA
关键词
giant vesicles; nanoparticles; photothermal effect; plasmonic properties; self-assembly; POLYMER VESICLES; DRUG-DELIVERY; GOLD NANORODS; LIPOSOMES; ENCAPSULATION; FABRICATION; MICELLE;
D O I
10.1002/anie.201208425
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The hydrodynamics of laminar flow in a microfluidic device has been used to control the continuous self-assembly of gold nanoparticles (NPs) tethered with amphiphilic block copolymers. Spherical micelles, giant vesicles (500 nm-2.0 μm), or disk-like micelles could be formed by varying the flow rates of fluids. Such vesicles can release encapsulated hydrophilic species by using near-IR light (see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2463 / 2468
页数:6
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