Invasive infections caused by Blastoschizomyces capitatus and Scedosporium spp.

被引:65
作者
Bouza, E [1 ]
Muñoz, P [1 ]
机构
[1] Univ Complutense, Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & E Infecciosas, Madrid 28007, Spain
关键词
Blastoschizomyces capitatus; Scedosporium prolificans; S; apiospermum; opportunistic infection invasive mycosis; neutropenia;
D O I
10.1111/j.1470-9465.2004.00842.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Blastoschizomyces capitatus, Scedosporium prolificans and S. apiospermum are emerging fungal pathogens that may cause disseminated disease in neutropenic patients. They can present as fever resistant to antibiotics and to wide-spectrum antifungal agents, although they may involve almost every organ. The proportion of recovery from blood cultures is high and they are characteristically resistant to most antifungal agents. Prognosis is poor unless patients recover from neutropenia. Voriconazole has good in-vitro activity and is currently the drug of choice for these infections.
引用
收藏
页码:76 / 85
页数:10
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