Biology of stem cells: an overview

被引：82

作者：

Chagastelles, Pedro C. ^{[1
]}

Nardi, Nance B. ^{[1
,2
]}

机构：

[1] Univ Fed Rio Grande do Sul, Dept Genet, BR-91501970 Porto Alegre, RS, Brazil

[2] Univ Luterana Brasil, Postgrad Program Genet & Mol Diag, Canoas, Brazil

来源：

KIDNEY INTERNATIONAL SUPPLEMENTS | 2011年 / 1卷 / 03期

关键词：

adult stem cells; biological characteristics; cell therapy; embryonic stem cells; human diseases;

D O I：

10.1038/kisup.2011.15

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

100201 [内科学]; 100221 [泌尿外科学];

摘要：

Stem cells are defined as precursor cells that have the capacity to self-renew and to generate multiple mature cell types. Only after collecting and culturing tissues is it possible to classify cells according to this operational concept. This difficulty in identifying stem cells in situ, without any manipulation, limits the understanding of their true nature. This review aims at presenting, to health professionals interested in this area, an overview on the biology of embryonic and adult stem cells, and their therapeutic potential.

引用

页码：63 / 67

页数：5

共 18 条

[1]

Attributes of adult stem cells [J].

Alison, M. R. ;

Islam, S. .

JOURNAL OF PATHOLOGY, 2009, 217 (02) :144-160

[2]

Beyer Nardi N, 2006, HANDB EXP PHARM, V174, P249

[3]

Stem cells: Promises versus limitations [J].

Choumerianou, Despoina M. ;

Dimitriou, Helen ;

Kalmanti, Maria .

TISSUE ENGINEERING PART B-REVIEWS, 2008, 14 (01) :53-60

[4]

Mesenchymal stem cells reside in virtually all post-natal organs and tissues [J].

da Silva Meirelles, Lindolfo ;

Chagastelles, Pedro Cesar ;

Nardi, Nance Beyer .

JOURNAL OF CELL SCIENCE, 2006, 119 (11) :2204-2213

[5]

IVF and the history of stem cells - Embryo stem cells are poised to fulfil their considerable historical potential. [J].

Edwards, RG .

NATURE, 2001, 413 (6854) :349-351

[6]

Socializing with the neighbors: Stem cells and their niche [J].

Fuchs, E ;

Tumbar, T ;

Guasch, G .

CELL, 2004, 116 (06) :769-778

[7]

Do stem cells exist in the adult kidney? [J].

Gupta, Sandeep ;

Rosenberg, Mark E. .

AMERICAN JOURNAL OF NEPHROLOGY, 2008, 28 (04) :607-613

[8]

Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells [J].

Maherali, Nimet ;

Hochedlinger, Konrad .

CELL STEM CELL, 2008, 3 (06) :595-605

[9]

Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review [J].

Martin-Rendon, Enca ;

Brunskill, Susan J. ;

Hyde, Chris J. ;

Stanworth, Simon J. ;

Mathur, Anthony ;

Watt, Suzanne M. .

EUROPEAN HEART JOURNAL, 2008, 29 (15) :1807-1818

[10]

Methodology, biology and clinical applications of mesenchymal stem cells [J].

Meirelles, Lindolfo da Silva ;

Nardi, Nance Beyer .

FRONTIERS IN BIOSCIENCE-LANDMARK, 2009, 14 :4281-4298

← 1 2 →