Electrochemical analysis in picoliter microvials

被引：124

作者：

Clark, RA ^{[1
]}

Hietpas, PB ^{[1
]}

Ewing, AG ^{[1
]}

机构：

[1] PENN STATE UNIV, DEPT CHEM, UNIVERSITY PK, PA 16802 USA

来源：

ANALYTICAL CHEMISTRY | 1997年 / 69卷 / 02期

关键词：

D O I：

10.1021/ac960559a

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Lithographically fabricated templates have been used to imprint picoliter to femtoliter microvials in polystyrene. The clear microvials produced in conjunction with a transmission optical microscope and micromanipulators make it possible to handle volumes as small as 1 pt. Voltammetry has been carried out in these well-defined microenvironments with restriction of reagents near the electrode surface. Ferrocenecarboxylic acid has been utilized to characterize the electrochemical response in these ultrasmall volumes. Sigmoidal voltammograms (0.4-2 V/s) are obtained for vial sizes down to 1 pL.

引用

页码：259 / 263

页数：5

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