Glucose biosensor based on gold nanoparticle-catalyzed luminol electrochemiluminescence on a three-dimensional sol-gel network

被引：100

作者：

Liu, Xiaoqing ^{[1
,2
]}

Niu, Wenxin ^{[1
,2
]}

Li, Haijuan ^{[1
,2
]}

Han, Shuang ^{[1
,2
]}

Hu, Lianzhe ^{[1
,2
]}

Xu, Guobao ^{[1
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing 100864, Peoples R China

来源：

ELECTROCHEMISTRY COMMUNICATIONS | 2008年 / 10卷 / 09期

基金：

中国国家自然科学基金;

关键词：

electrochemiluminescence; biosensor; gold nanoparticles; luminol; glucose;

D O I：

10.1016/j.elecom.2008.06.009

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

An electrochemiluminescent glucose biosensor was proposed based on gold nanoparticle-catalyzed luminol electrochemiluminescence (ECL). Gold nanoparticles were self-assembled onto silica sol-gel network, and then glucose oxidase was adsorbed on the surface of gold nanoparticles. The surface assembly process and the electrochemistry and ECL behaviors of the biosensor were investigated. The assembled gold nanoparticles could efficiently electrocatalyze luminol ECL ECL intensity of the biosensor depended on scan rate, luminol concentration, and size of gold nanoparticles. The response of the ECL biosensor was linear over the range 1 mu M to 5 mM with a detection limit of 0.2 mu M glucose and showed satisfying reproducibility, stability and selectivity. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：1250 / 1253

页数：4

共 40 条

[1] Novel electrochemical interfaces with a tunable kinetic barrier by self-assembling organically modified silica gel and gold nanoparticles [J].

Bharathi, S ;

Nogami, M ;

Ikeda, S .

LANGMUIR, 2001, 17 (01) :1-4

[2] Optical biosensors [J].

Borisov, Sergey M. ;

Wolfbeis, Otto S. .

CHEMICAL REVIEWS, 2008, 108 (02) :423-461

[3] Morphology-dependent electrochemistry of cytochrome c at Au colloid-modified SnO2 electrodes [J].

Brown, KR ;

Fox, AP ;

Natan, MJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (05) :1154-1157

[4] An electrochemiluminescent sensor for glucose employing a modified carbon nanotube paste electrode [J].

Chen, Jinhua ;

Lin, Zhenyu ;

Chen, Guonan .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2007, 388 (02) :399-407

[5] Multichannel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticle self-assembled electrode [J].

Cui, H ;

Xu, Y ;

Zhang, ZF .

ANALYTICAL CHEMISTRY, 2004, 76 (14) :4002-4010

[6] Synthesis, characterization, and electrochemiluminescence of luminol-reduced gold nanoparticles and their application in a hydrogen peroxide sensor [J].

Cui, Hua ;

Wang, Wei ;

Duan, Chun-Feng ;

Dong, Yong-Ping ;

Guo, Ji-Zhao .

CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (24) :6975-6984

[7] Comparative studies on electrogenerated chemiluminescence of luminol on gold nanoparticle modified electrodes [J].

Dong, Yong-Ping ;

Cui, Hua ;

Xu, Yang .

LANGMUIR, 2007, 23 (02) :523-529

[8] ORGANIZATION OF AU COLLOIDS AS MONOLAYER FILMS ONTO ITO GLASS SURFACES - APPLICATION OF THE METAL COLLOID FILMS AS BASE INTERFACES TO CONSTRUCT REDOX-ACTIVE MONOLAYERS [J].

DORON, A ;

KATZ, E ;

WILLNER, I .

LANGMUIR, 1995, 11 (04) :1313-1317

[9] Recent applications of electrogenerated chemiluminescence in chemical analysis [J].

Fähnrich, KA ;

Pravda, M ;

Guilbault, GG .

TALANTA, 2001, 54 (04) :531-559

[10]

Faulkner L.R, 1977, ELECTROANALYTICAL CH, V10

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