One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water

被引：42

作者：

Abbas, M ^{[1
]}

Bethke, J ^{[1
]}

Wessjohann, LA ^{[1
]}

机构：

[1] Leibniz Inst Plant Biochem, Dept Bioorgan Chem, D-06120 Halle, Germany

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 05期

关键词：

D O I：

10.1039/b514597j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.

引用

页码：541 / 543

页数：3

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