Mini-proteins Trp the light fantastic

被引：53

作者：

Gellman, SH

Woolfson, DN

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

[2] Univ Sussex, Sch Biol Sci, Ctr Biomol Design & Drug Dev, Brighton BN1 9QG, E Sussex, England

来源：

NATURE STRUCTURAL BIOLOGY | 2002年 / 9卷 / 06期

关键词：

D O I：

10.1038/nsb0602-408

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new 20-residue peptide represents the smallest example to date of cooperatively folded tertiary structure. This achievement provides a new tool for elucidating protein conformational preferences. The mini-protein should serve as a fruitful platform for protein design.

引用

页码：408 / 410

页数：4

共 15 条

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