Uniquely folded mini-protein motifs

被引:43
作者
Imperiali, B [1 ]
Ottesen, JJ [1 ]
机构
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源
JOURNAL OF PEPTIDE RESEARCH | 1999年 / 54卷 / 03期
关键词
mini-protein motif; protein design; helix bundle; Betanova; BBA motif; charybdotoxin;
D O I
10.1034/j.1399-3011.1999.00121.x
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Mini-proteins containing fewer than 40 amino acids provide simple model systems for studying protein folding and stability as well as serving as scaffolds for the rational design of new functional motifs. This article reviews current progress on the design and characterization of discretely folded mini-protein motifs.
引用
收藏
页码:177 / 184
页数:8
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