Silencing HIV-1 in vivo

被引：24

作者：

Kirchhoff, Frank ^{[1
]}

机构：

[1] Univ Ulm, Inst Virol, D-89081 Ulm, Germany

来源：

CELL | 2008年 / 134卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.cell.2008.08.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.

引用

收藏

页码：566 / 568

页数：4

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