Familial risk among patients with endometriosis

被引：38

作者：

Dos Reis, RM ^{[1
]}

De Sá, MFS ^{[1
]}

De Moura, MD ^{[1
]}

Nogueira, AA ^{[1
]}

Ribeiro, JU ^{[1
]}

Ramos, ES ^{[1
]}

Ferriani, RA ^{[1
]}

机构：

[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Gynecol & Obstet, BR-14049900 Ribeirao Preto, Brazil

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 1999年 / 16卷 / 09期

关键词：

dysmenorrhea; endometriosis; hereditary disease; laparoscopy;

D O I：

10.1023/A:1020559201968

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose: The objective of the present study teas to determine the prevalence of endometriosis among the relatives of patients with confirmed endometriosis. Methods: We analyzed the prevalence of endometriosis among first, second-, and third-degree relatives in a group of 101 patients with varying symptoms related to endometriosis seen at two public hospitals and submitted to laparoscopy and/or laparotomy. The control group consisted of 43 women submitted to laparoscopy without a diagnosis of endometriosis. Results: Among the patients with endometriosis, we detected nine families with a positive history of endometriosis, comprising one mother, six sisters, three aunts, and two cousins, as opposed to no case among the controls. Conclusions: These data confirm a familial tendency for endometriosis and suggest that this disorder has a genetic basis.

引用

页码：500 / 503

页数：4

共 11 条

[1] ADENOMYOSIS - EVIDENCE FOR GENETIC CAUSE [J].