A general strategy for improving enantiomeric purities via the tandem use of mirror-image catalysts

被引：17

作者：

Faller, JW ^{[1
]}

Lavoie, AR ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06520 USA

来源：

ORGANOMETALLICS | 2002年 / 21卷 / 09期

关键词：

D O I：

10.1021/om010960+

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In situations where the asymmetric transfer hydrogenation catalysis of a given ketone gives moderate, though insufficiently high ee, the enantiomeric purity of the resulting alcohol can be enhanced via a subsequent asymmetric dehydrogenation with the antipode of the catalyst. Herein, we report on the theoretical and experimental aspects of this strategy.

引用

页码：2010 / 2012

页数：3

共 35 条

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