Glycolipids from sponges.: Part 16.: Discoside, a rare myo-inositol-containing glycolipid from the Caribbean sponge Discodermia dissoluta

被引：11

作者：

Barbieri, L ^{[1
]}

Costantino, V ^{[1
]}

Fattorusso, E ^{[1
]}

Mangoni, A ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 10期

关键词：

D O I：

10.1021/np050241q

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Discoside (1a), a glycolipid composed of 4,6-O-diacylated mannose attached to the 2-hydroxyl group of a myo-inositol unit, was isolated as a mixture of homologues from the marine sponge Discodermia dissoluta. The complete stereostructure of this new glycolipid was solved by interpretation of mass spectrometric and NMR data and CD analysis of degradation products.

引用

页码：1527 / 1530

页数：4

共 10 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].

AGRAWAL, PK ;

JAIN, DC ;

GUPTA, RK ;

THAKUR, RS .

PHYTOCHEMISTRY, 1985, 24 (11) :2479-2496

[2] Glycolipids from sponges.: Part 8:: Plakopolyprenoside from the marine sponge Plakortis simplex.: An improved procedure for isolation of glycolipids as peracetyl derivatives [J].

Costantino, V ;

Fattorusso, E ;

Mangoni, A ;

Di Rosa, M ;

Ianaro, A .

TETRAHEDRON, 2000, 56 (10) :1393-1395

[3]

COSTANTINO V, UNPUB J MED CHEM

[4] Structural study of the LipoMannans from Mycobacterium bovis BCG:: Characterisation of multiacylated forms of the phosphatidyl-myo-inositol anchor [J].

Gilleron, M ;

Nigou, J ;

Cahuzac, B ;

Puzo, G .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 285 (05) :2147-2160

[5] DISCODERMOLIDE - A NEW BIOACTIVE POLYHYDROXYLATED LACTONE FROM THE MARINE SPONGE DISCODERMIA-DISSOLUTA [J].

GUNASEKERA, SP ;

GUNASEKERA, M ;

LONGLEY, RE ;

SCHULTE, GK .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (16) :4912-4915

[6]

LOWARY LT, 2001, GLYCOSCIENCE, V3, P2005

[7]

ODHAM G, 1972, BIOCH APPLICATIONS M, P211

[8] Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei [J].

Piel, J ;

Hui, DQ ;

Wen, GP ;

Butzke, D ;

Platzer, M ;

Fusetani, N ;

Matsunaga, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (46) :16222-16227

[9]

PROTTEY C, 1968, J BIOL CHEM, V243, P6169

[10] Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery [J].

Salomon, CE ;

Magarvey, NA ;

Sherman, DH .

NATURAL PRODUCT REPORTS, 2004, 21 (01) :105-121

← 1 →