GenoWatch: a disease gene mining browser for association study

被引：10

作者：

Chen, Yan-Hau ^{[1
]}

Liu, Chuan-Kun ^{[1
]}

Chang, Shu-Chuan ^{[1
]}

Lin, Yi-Jung ^{[1
]}

Tsai, Ming-Fang ^{[1
]}

Chen, Yuan-Tsong ^{[1
,2
]}

Yao, Adam ^{[1
,2
]}

机构：

[1] Acad Sinica, NGC, Taipei 11529, Taiwan

[2] Acad Sinica, Inst Biomed Sci, Taipei 11529, Taiwan

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

关键词：

D O I：

10.1093/nar/gkn214

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A human gene association study often involves several genomic markers such as single nucleotide polymorphisms (SNPs) or short tandem repeat polymorphisms, and many statistically significant markers may be identified during the study. GenoWatch can efficiently extract up-to-date information about multiple markers and their associated genes in batch mode from many relevant biological databases in real-time. The comprehensive gene information retrieved includes gene ontology, function, pathway, disease, related articles in PubMed and so on. Subsequent SNP functional impact analysis and primer design of a target gene for re-sequencing can also be done in a few clicks. The presentation of results has been carefully designed to be as intuitive as possible to all users. The GenoWatch is available at the website http://genepipe.ngc.sinica.edu.tw/genowatch.

引用

页码：W336 / W340

页数：5

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