Advanced organic synthesis using microreactor technology

被引:285
作者
Ahmed-Omer, Batoul
Brandt, Johan C.
Wirth, Thomas
机构
[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales
[2] Cardiff Univ, Cardiff Sch Engn, Lab Appl Microsyst, Cardiff CF24 3TF, S Glam, Wales
关键词
D O I
10.1039/b615072a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Organic synthesis in microreactors is a novel way of performing reactions in a highly controlled way. The benefits of microreactors result from their physical properties, such as enhanced mass and heat transfer as well as regular flow profiles leading to improved yields with increased selectivities.
引用
收藏
页码:733 / 740
页数:8
相关论文
共 73 条
  • [1] Discovering new water soluble catalysts for the liquid/liquid isomerization of allylic alcohols using microdevices
    Abdallah, R
    Ireland, T
    de Bellefon, C
    [J]. CHEMIE INGENIEUR TECHNIK, 2004, 76 (05) : 633 - 637
  • [2] Enhancement of reaction rates by segmented fluid flow in capillary scale reactors
    Ahmed, Batoul
    Barrow, David
    Wirth, Thomas
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2006, 348 (09) : 1043 - 1048
  • [3] The polymer incarcerated method for the preparation of highly active heterogeneous palladium catalysts
    Akiyama, R
    Kobayashi, S
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (12) : 3412 - 3413
  • [4] Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles
    Baumann, Marcus
    Baxendale, Ian R.
    Ley, Steven V.
    Smith, Christoper D.
    Tranmer, Geoffrey K.
    [J]. ORGANIC LETTERS, 2006, 8 (23) : 5231 - 5234
  • [5] Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations
    Baxendale, Ian R.
    Griffiths-Jones, Charlotte M.
    Ley, Steven V.
    Tranmer, Geoffrey K.
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2006, 12 (16) : 4407 - 4416
  • [6] A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly
    Baxendale, Ian R.
    Deeley, Jon
    Griffiths-Jones, Charlotte M.
    Ley, Steven V.
    Saaby, Steen
    Tranmer, Geoffrey K.
    [J]. CHEMICAL COMMUNICATIONS, 2006, (24) : 2566 - 2568
  • [7] Enantioselective catalysis and analysis on a chip
    Belder, D
    Ludwig, M
    Wang, LW
    Reetz, MT
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (15) : 2463 - 2466
  • [8] Microfluidics with droplets
    Belder, D
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (23) : 3521 - 3522
  • [9] BELDER D, 2006, ANGEW CHEM, V118, P253
  • [10] Elemental fluorine - Part 13. Gas-liquid thin film microreactors for selective direct fluorination
    Chambers, RD
    Holling, D
    Spink, RCH
    Sandford, G
    [J]. LAB ON A CHIP, 2001, 1 (02): : 132 - 137