Gene diversity of chimpanzee ABO blood group genes elucidated from intron 6 sequences

被引：7

作者：

Kitano, T

Noda, R

Sumiyama, K

Ferrell, RE

Saitou, N ^{[1
]}

机构：

[1] Natl Inst Genet, Lab Evolutionary Genet, Mishima, Shizuoka 4118540, Japan

[2] Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USA

来源：

JOURNAL OF HEREDITY | 2000年 / 91卷 / 03期

关键词：

D O I：

10.1093/jhered/91.3.211

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The human and nonhuman primate ABO blood group gene shows relatively large numbers of nucleotide differences around the exon 7 region. In this study we determined intron 6 sequences for 9 alleles of common chimpanzee and for 3 alleles of bonobo to estimate nucleotide diversities among them. Sequence length polymorphisms are observed in this region as a repeat appears one to five times. From a phylogenetic network of intron 6 sequences of ABO blood group genes for humans, common chimpanzee, and bonobo, parallel substitutions and/or some kinds of convergent events are predicted in the chimpanzee lineage. We also estimated nucleotide diversities for common chimpanzee and bonobo ABO blood group genes; these values were 0.219% and 0.208%, respectively.

引用

页码：211 / 214

页数：4

共 24 条

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