Stepwise solid-phase synthesis of serine-, tyrosine- and homoserine-nucleopeptides.

被引：6

作者：

Beltran, M ^{[1
]}

Maseda, M ^{[1
]}

Perez, Y ^{[1
]}

Robles, J ^{[1
]}

Pedroso, E ^{[1
]}

Grandas, A ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC QUIM,DEPT QUIM ORGAN,E-08028 BARCELONA,SPAIN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 7-9期

关键词：

D O I：

10.1080/07328319708006212

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hydroxylated amino acids can be introduced in nucleopeptides using the acetyl group for their side chain protection. Base-stable nucleopeptide analogues are obtained if homoserine is used as the linking residue.

引用

页码：1487 / 1488

页数：2

共 6 条

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LIU, LF
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1989, 58 : 351 - 375
[3] PEPTIDE-OLIGONUCLEOTIDE HYBRIDS WITH N-ACYLPHOSPHORAMIDATE LINKAGES
ROBLES, J
PEDROSO, E
GRANDAS, A
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[4] STEPWISE SOLID-PHASE SYNTHESIS OF THE NUCLEOPEPTIDE PHAC-PHE-VAL-SER(P(3')ACT)-GLY-OH
ROBLES, J
PEDROSO, E
GRANDAS, A
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (09) : 2482 - 2486
[5] SOLID-PHASE SYNTHESIS OF A NUCLEOPEPTIDE FROM THE LINKING SITE OF ADENOVIRUS-2 NUCLEOPROTEIN, -SER(P5'CATCAT)-GLY-ASP- - CONVERGENT VERSUS STEPWISE STRATEGY
ROBLES, J
PEDROSO, E
GRANDAS, A
[J]. NUCLEIC ACIDS RESEARCH, 1995, 23 (20) : 4151 - 4161
[6] SALAS M, 1988, BACTERIOPHAGES, V1, P169

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