Inhibition by ajoene of skin-tumor promotion in mice

被引：33

作者：

Nishikawa, T ^{[1
]}

Yamada, N ^{[1
]}

Hattori, A ^{[1
]}

Fukuda, H ^{[1
]}

Fujino, T ^{[1
]}

机构：

[1] Nagoya Seiraku Co Ltd, Cent Inst, Biodev Div, Tempaku Ku, Nagoya, Aichi 4680065, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2002年 / 66卷 / 10期

关键词：

antitumor effect; cancer chemoprevention; ajoene; garlic; Allium sativum;

D O I：

10.1271/bbb.66.2221

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ajoene, a major compound containing sulfur in oil-macerated garlic products, inhibited in a two-stage carcinogenesis test on mouse skin. Treatment with ajoene suppressed skin tumor formation, depending on the amount. In particular, the group treated with 250 mug of ajoene had only 4.9% the number of tumors per mouse compared with the control group at 18 weeks.

引用

页码：2221 / 2223

页数：3

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