Frailty Consensus: A Call to Action

被引:2706
作者
Morley, John E. [1 ]
Vellas, Bruno [2 ,3 ]
van Kan, G. Abellan [2 ,3 ]
Anker, Stefan D. [4 ,5 ]
Bauer, Juergen M. [6 ,7 ]
Bernabei, Roberto [8 ]
Cesari, Matteo [2 ,3 ]
Chumlea, W. C. [9 ]
Doehner, Wolfram [4 ,10 ]
Evans, Jonathan
Fried, Linda P. [11 ,12 ]
Guralnik, Jack M. [13 ]
Katz, Paul R. [14 ,15 ]
Malmstrom, Theodore K. [1 ,16 ]
McCarter, Roger J. [17 ]
Gutierrez Robledo, Luis M. [18 ]
Rockwood, Ken [19 ]
von Haehling, Stephan [20 ]
Vandewoude, Maurits F. [21 ]
Walston, Jeremy [22 ]
机构
[1] St Louis Univ, Sch Med, Div Geriatr Med, St Louis, MO 63104 USA
[2] Univ Toulouse 3, INSERM UMR 1027, F-31062 Toulouse, France
[3] Ctr Hosp Univ Toulouse, Gerontopole, Toulouse, France
[4] Charite, Dept Cardiol, Berlin, Germany
[5] IRCCS San Rafaette, Ctr Clin & Basic Res, Rome, Italy
[6] Carl von Ossietzky Univ Oldenburg, Geriatr Ctr, Oldenburg, Germany
[7] Univ Erlangen Nurnberg, Inst Biomed Ageing, D-91054 Erlangen, Germany
[8] Univ Cattolica Sacro Cuore, Dept Geriatr Neurosc & Orthopaed, I-00168 Rome, Italy
[9] Wright State Univ, Boonshoft Sch Med, Lifespan Hlth Res Ctr, Dept Community Hlth, Dayton, OH 45435 USA
[10] Charite, Ctr Stroke Res, D-13353 Berlin, Germany
[11] Columbia Univ, Joseph L Mailman Sch Publ Hlth, New York, NY USA
[12] Columbia Univ, Coll Phys & Surg, New York, NY USA
[13] Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA
[14] Baycrest Hlth Sci Ctr, Toronto, ON, Canada
[15] Univ Toronto, Toronto, ON, Canada
[16] St Louis Univ, Sch Med, Dept Neurol & Psychiat, St Louis, MO USA
[17] Penn State Univ, University Pk, PA 16802 USA
[18] Inst Nacl Salud Mexico, Inst Nacl Geriatria, Mexico City, DF, Mexico
[19] Dalhousie Univ, Halifax, NS, Canada
[20] Charite, Dept Cardiol, D-13353 Berlin, Germany
[21] Univ Antwerp, ZNA St Elizabeth Hosp, Dept Geriatr, B-2020 Antwerp, Belgium
[22] Johns Hopkins Univ, Div Geriatr Med & Gerontol, Baltimore, MD USA
关键词
Frailty; physical frailty; rapid screening tests; weight loss; comorbidities; OLDER PERSONS; VITAMIN-D; PROTEIN SUPPLEMENTATION; ELDERLY-PEOPLE; NURSING-HOME; DEFICIT ACCUMULATION; FUNCTIONAL DECLINE; CLINICAL-PRACTICE; POOLED ANALYSIS; PRIMARY-CARE;
D O I
10.1016/j.jamda.2013.03.022
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Frailty is a clinical state in which there is an increase in an individual's vulnerability for developing increased dependency and/or mortality when exposed to a stressor. Frailty can occur as the result of a range of diseases and medical conditions. A consensus group consisting of delegates from 6 major international, European, and US societies created 4 major consensus points on a specific form of frailty: physical frailty. 1. Physical frailty is an important medical syndrome. The group defined physical frailty as "a medical syndrome with multiple causes and contributors that is characterized by diminished strength, endurance, and reduced physiologic function that increases an individual's vulnerability for developing increased dependency and/or death." 2. Physical frailty can potentially be prevented or treated with specific modalities, such as exercise, protein-calorie supplementation, vitamin D, and reduction of polypharmacy. 3. Simple, rapid screening tests have been developed and validated, such as the simple FRAIL scale, to allow physicians to objectively recognize frail persons. 4. For the purposes of optimally managing individuals with physical frailty, all persons older than 70 years and all individuals with significant weight loss (>= 5%) due to chronic disease should be screened for frailty. Copyright (c) 2013 - American Medical Directors Association, Inc.
引用
收藏
页码:392 / 397
页数:6
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