The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin

被引：80

作者：

Slominski, A ^{[1
]}

Ermak, G ^{[1
]}

Hwang, J ^{[1
]}

Mazurkiewicz, J ^{[1
]}

Corliss, D ^{[1
]}

Eastman, A ^{[1
]}

机构：

[1] ALBANY MED COLL,DEPT MICROBIOL MOLEC GENET & IMMUNOL,ALBANY,NY 12208

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 1996年 / 1289卷 / 02期

基金：

美国国家科学基金会;

关键词：

corticotropin releasing hormone receptor; corticotropin releasing hormone; proopiomelanocortin; hair growth; (C57BL/6 mouse);

D O I：

10.1016/0304-4165(95)00159-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The proopiomelanocortin (POMC) and the corticotropin releasing hormone receptor (CRH-R) genes are expressed in the skin of the C57BL/6 mouse throughout the entire hair cycle, and CRH immunoreactivity is present in the pilosebaceous unit of the hair follicle and the epidermis. These findings suggest that some components of hypothalamo-pituitary axis are operating in mouse skin.

引用

页码：247 / 251

页数：5

共 24 条

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