Cellular mechanisms of infarct size reduction with ischemic preconditioning - Role of calcium?

被引：27

作者：

Przyklenk, K

Simkhovich, BZ

Bauer, B

Hata, K

Zhao, L

Elliott, GT

Kloner, RA

机构：

[1] Hosp Good Samaritan, Inst Heart, Los Angeles, CA 90017 USA

[2] Univ So Calif, Dept Med, Cardiol Sect, Los Angeles, CA 90017 USA

[3] RIBI Immunochem Res Inc, Hamilton, MT 59840 USA

来源：

HEART IN STRESS | 1999年 / 874卷

关键词：

D O I：

10.1111/j.1749-6632.1999.tb09236.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Brief episodes of ischemia protect or "precondition" the heart and reduce infarct size caused by a subsequent sustained ischemic insult. Despite a decade of intensive investigation, the cellular mechanism(s) responsible for this paradoxical protection remain poorly understood. In this review, we focus on the emerging concept that alterations in intracellular calcium homeostasis mag participate in either triggering and/or mediating Infarct size reduction with preconditioning.

引用

页码：192 / 210

页数：19

共 99 条

[1] INTRACELLULAR CALCIUM AND VENTRICULAR-FUNCTION - EFFECTS OF NISOLDIPINE ON GLOBAL-ISCHEMIA IN THE ISOVOLUMIC, CORONARY-PERFUSED HEART
AMENDE, I
BENTIVEGNA, LA
ZEIND, AJ
WENZLAFF, P
GROSSMAN, W
MORGAN, JP
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1992, 89 (06) : 2060 - 2065
[2] PRECONDITIONING OF PERFUSED RAT-HEART INHIBITS REPERFUSION-INDUCED RELEASE OF INOSITOL(1,4,5)TRISPHOSPHATE
ANDERSON, KE
WOODCOCK, EA
[J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1995, 27 (11) : 2421 - 2431
[3] PRECONDITIONING OF ISOLATED RABBIT CARDIOMYOCYTES - EFFECTS OF GLYCOLYTIC BLOCKADE, PHORBOL ESTERS, AND ISCHEMIA
ARMSTRONG, S
GANOTE, CE
[J]. CARDIOVASCULAR RESEARCH, 1994, 28 (11) : 1700 - 1706
[4] Protein phosphatase inhibitors calyculin A and fostriecin protect rabbit cardiomyocytes in late ischemia
Armstrong, SC
Gao, W
Lane, JR
Ganote, CE
[J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1998, 30 (01) : 61 - 73
[5] PKC-independent inhibition of cardiac L-type Ca2+ channel current by phorbol esters
Asai, T
Shuba, LM
Pelzer, DJ
McDonald, TF
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1996, 270 (02): : H620 - H627
[6] ISCHEMIC PRECONDITIONING ATTENUATES ACIDOSIS AND POSTISCHEMIC DYSFUNCTION IN ISOLATED RAT-HEART
ASIMAKIS, GK
INNERSMCBRIDE, K
MEDELLIN, G
CONTI, VR
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 263 (03): : H887 - H894
[7] Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart
Baines, CP
Wang, L
Cohen, MV
Downey, JM
[J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1998, 30 (02) : 383 - 392
[8] PRECONDITIONING AGAINST MYOCARDIAL DYSFUNCTION AFTER ISCHEMIA AND REPERFUSION BY AN ALPHA-1-ADRENERGIC MECHANISM
BANERJEE, A
LOCKEWINTER, C
ROGERS, KB
MITCHELL, MB
BREW, EC
CAIRNS, CB
BENSARD, DD
HARKEN, AH
[J]. CIRCULATION RESEARCH, 1993, 73 (04) : 656 - 670
[9] Preconditioning-induced cardioprotection and release of the second messenger inositol (1,4,5)-trisphosphate are both abolished by neomycin in rabbit heart
Bauer, B
Simkhovich, BZ
Kloner, RA
Przyklenk, K
[J]. BASIC RESEARCH IN CARDIOLOGY, 1999, 94 (01) : 31 - 40
[10] THE PROGNOSTIC-SIGNIFICANCE OF ANGINA-PECTORIS PRECEDING THE OCCURRENCE OF A 1ST ACUTE MYOCARDIAL-INFARCTION IN 4166 CONSECUTIVE HOSPITALIZED-PATIENTS
BEHAR, S
REICHERREISS, H
ABINADER, E
AGMON, J
FRIEDMAN, Y
BARZILAI, J
KAPLINSKY, E
KAULI, N
KISHON, Y
PALANT, A
PELED, B
RABINOVICH, B
REISIN, L
SCHLESINGER, Z
ZAHAVI, I
ZION, M
GOLDBOURT, U
[J]. AMERICAN HEART JOURNAL, 1992, 123 (06) : 1481 - 1486

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