Aging and attentional guidance during visual search: Functional neuroanatomy by positron emission tomography

被引:64
作者
Madden, DJ
Turkington, TG
Provenzale, JM
Denny, LL
Langley, LK
Hawk, TC
Coleman, RE
机构
[1] Duke Univ, Med Ctr, Ctr Study Aging & Human Dev, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA
[4] Duke Univ, Dept Biomed Engn, Durham, NC 27710 USA
关键词
D O I
10.1037//0882-7974.17.1.24
中图分类号
R4 [临床医学]; R592 [老年病学];
学科分类号
1002 ; 100203 ; 100602 ;
摘要
Positron emission tomography (PET) was used to examine adult age differences in neural activation during visual search. Target detection was less accurate for older adults than fur younger adults, but both age groups were successful in using color to guide attention to a subset of display items. Increasing Perceptual difficulty led to greater activation of occipitotemporal cortex for younger adults than fur older adults, apparently as the result of older adults maintaining higher levels of activation within the easier task conditions, The results suggest that compensation for age-related decline in the efficiency of occipitotemporal cortical functioning was implemented by changes in the relative level of activation within this visual processing pathway, rather than by the recruitment of other cortical regions.
引用
收藏
页码:24 / 43
页数:20
相关论文
共 86 条
[21]   DISSOCIATION OF OBJECT AND SPATIAL VISION IN HUMAN EXTRASTRIATE CORTEX - AGE-RELATED-CHANGES IN ACTIVATION OF REGIONAL CEREBRAL BLOOD-FLOW MEASURED WITH [O-15]WATER AND POSITRON EMISSION TOMOGRAPHY [J].
GRADY, CL ;
HAXBY, JV ;
HORWITZ, B ;
SCHAPIRO, MB ;
RAPOPORT, SI ;
UNGERLEIDER, LG ;
MISHKIN, M ;
CARSON, RE ;
HERSCOVITCH, P .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1992, 4 (01) :23-34
[22]  
Grady CL, 1996, HUM BRAIN MAPP, V4, P227, DOI 10.1002/(SICI)1097-0193(1996)4:4<227::AID-HBM1>3.0.CO
[23]  
2-5
[24]   Brain imaging and age-related changes in cognition [J].
Grady, CL .
EXPERIMENTAL GERONTOLOGY, 1998, 33 (7-8) :661-673
[25]  
HANDY TC, 2001, HDB FUNCTIONAL NEURO, P75
[26]  
Hartley A. A., 1992, HDB AGING COGNITION, P3, DOI DOI 10.1017/S0714980800012332
[27]  
Hartley AA, 2000, MICROSC RES TECHNIQ, V51, P45, DOI 10.1002/1097-0029(20001001)51:1<45::AID-JEMT5>3.0.CO
[28]  
2-O
[29]   DISSOCIATION OF OBJECT AND SPATIAL VISUAL PROCESSING PATHWAYS IN HUMAN EXTRASTRIATE CORTEX [J].
HAXBY, JV ;
GRADY, CL ;
HORWITZ, B ;
UNGERLEIDER, LG ;
MISHKIN, M ;
CARSON, RE ;
HERSCOVITCH, P ;
SCHAPIRO, MB ;
RAPOPORT, SI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) :1621-1625
[30]  
HAXBY JV, 1994, J NEUROSCI, V14, P6336