Biased Gene Fractionation and Dominant Gene Expression among the Subgenomes of Brassica rapa

被引：211

作者：

Cheng, Feng ^{[1
]}

Wu, Jian ^{[1
]}

Fang, Lu ^{[1
]}

Sun, Silong ^{[1
]}

Liu, Bo ^{[1
]}

Lin, Ke ^{[2
]}

Bonnema, Guusje ^{[2
]}

Wang, Xiaowu ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100193, Peoples R China

[2] Lab Plant Breeding, Wageningen, Netherlands

来源：

PLOS ONE | 2012年 / 7卷 / 05期

关键词：

SHORT READ ALIGNMENT; ARABIDOPSIS-THALIANA; DNA METHYLATION; GENOME SEQUENCE; DUPLICATION; EVOLUTION; POLYPLOIDS; PLANTS;

D O I：

10.1371/journal.pone.0036442

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Polyploidization, both ancient and recent, is frequent among plants. A "two-step theory'' was proposed to explain the meso-triplication of the Brassica "A'' genome: Brassica rapa. By accurately partitioning of this genome, we observed that genes in the less fractioned subgenome (LF) were dominantly expressed over the genes in more fractioned subgenomes (MFs: MF1 and MF2), while the genes in MF1 were slightly dominantly expressed over the genes in MF2. The results indicated that the dominantly expressed genes tended to be resistant against gene fractionation. By re-sequencing two B. rapa accessions: a vegetable turnip (VT117) and a Rapid Cycling line (L144), we found that genes in LF had less non-synonymous or frameshift mutations than genes in MFs; however mutation rates were not significantly different between MF1 and MF2. The differences in gene expression patterns and on-going gene death among the three subgenomes suggest that "two-step'' genome triplication and differential subgenome methylation played important roles in the genome evolution of B. rapa.

引用

页数：9

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