Natural products and the treatment of leukemia

被引:18
作者
Hamblin, T [1 ]
机构
[1] Univ Southampton, Royal Bournemouth Hosp, Dept Haematol, Bournemouth BH7 7DW, Dorset, England
关键词
CLL; EGCG; natural products; polyphenols; green tea; bioflavonoids;
D O I
10.1016/j.leukres.2005.10.023
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Plants have been the source of many medicines in the pharmacopoeia. So much so that an industry has arisen selling plant extracts as health foods. To a great degree it operates over the internet and it chiefly caters to the worried well. However, cancer patients frequently take plant extracts in addition to their prescribed medicines. These extracts are not biologically inactive, and many have important pro-apoptotic effects on cancer cell-lines in vitro. In this issue a study of the in vivo effects of green tea extract in low grade lymphomas is reported. The results are sufficiently encouraging to initiate a formal clinical trial. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:649 / 650
页数:2
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