CLL;
EGCG;
natural products;
polyphenols;
green tea;
bioflavonoids;
D O I:
10.1016/j.leukres.2005.10.023
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 [肿瘤学];
摘要:
Plants have been the source of many medicines in the pharmacopoeia. So much so that an industry has arisen selling plant extracts as health foods. To a great degree it operates over the internet and it chiefly caters to the worried well. However, cancer patients frequently take plant extracts in addition to their prescribed medicines. These extracts are not biologically inactive, and many have important pro-apoptotic effects on cancer cell-lines in vitro. In this issue a study of the in vivo effects of green tea extract in low grade lymphomas is reported. The results are sufficiently encouraging to initiate a formal clinical trial. (c) 2005 Elsevier Ltd. All rights reserved.
机构:
Lincoln Univ, Inst Med Sci, Biomed Res Lab, Brayford Pool LN6 7TS, Lincs, EnglandLincoln Univ, Inst Med Sci, Biomed Res Lab, Brayford Pool LN6 7TS, Lincs, England
机构:Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
Lombard, C
;
Nagarkatti, M
论文数: 0引用数: 0
h-index: 0
机构:Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
Nagarkatti, M
;
Nagarkatti, PS
论文数: 0引用数: 0
h-index: 0
机构:
Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USAVirginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Matsui, J
;
Kiyokawa, N
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Kiyokawa, N
;
Takenouchi, H
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Takenouchi, H
;
Taguchi, T
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Taguchi, T
;
Suzuki, K
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Suzuki, K
;
Shiozawa, Y
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Shiozawa, Y
;
Saito, M
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Saito, M
;
Tang, WR
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Tang, WR
;
Katagiri, YU
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Katagiri, YU
;
Okita, H
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Okita, H
;
Fujimoto, J
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
机构:
Lincoln Univ, Inst Med Sci, Biomed Res Lab, Brayford Pool LN6 7TS, Lincs, EnglandLincoln Univ, Inst Med Sci, Biomed Res Lab, Brayford Pool LN6 7TS, Lincs, England
机构:Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
Lombard, C
;
Nagarkatti, M
论文数: 0引用数: 0
h-index: 0
机构:Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
Nagarkatti, M
;
Nagarkatti, PS
论文数: 0引用数: 0
h-index: 0
机构:
Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USAVirginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Matsui, J
;
Kiyokawa, N
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Kiyokawa, N
;
Takenouchi, H
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Takenouchi, H
;
Taguchi, T
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Taguchi, T
;
Suzuki, K
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Suzuki, K
;
Shiozawa, Y
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Shiozawa, Y
;
Saito, M
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Saito, M
;
Tang, WR
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Tang, WR
;
Katagiri, YU
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Katagiri, YU
;
Okita, H
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan
Okita, H
;
Fujimoto, J
论文数: 0引用数: 0
h-index: 0
机构:
Natl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, JapanNatl Res Inst Child Hlth & Dev, Dept Dev Biol, Setagaya Ku, Tokyo 1548535, Japan