Interleukin-10: a cytokine used by tumors to escape immunosurveillance

被引：91

作者：

Salazar-Onfray, F

机构：

[1] Univ Chile, Fac Med, Inst Biomed Sci, Program Immunol, Santiago 7, Chile

[2] Karolinska Hosp, Radiumhemmet, Dept Pathol & Oncol, S-10401 Stockholm, Sweden

来源：

MEDICAL ONCOLOGY | 1999年 / 16卷 / 02期

关键词：

D O I：

10.1007/BF02785841

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The mechanisms whereby malignant cells can elude the recognition of the immune system, by what is termed 'immunological escape', have attracted major attention of tumor immunologists during the past decade. In this review, the role of the immunosuppuessive cytokine interleukin-10 (IL-10) will be discussed as a strategy used by tumors to avoid recognition by cytotoxic T lymphocytes (CTL).

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页码：86 / 94

页数：9

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