Collagen hydrolysate based collagen/hydroxyapatite composite materials

被引：46

作者：

Ficai, Anton ^{[1
]}

Albu, Madalina Georgiana ^{[2
]}

Birsan, Mihaela ^{[1
]}

Sonmez, Maria ^{[1
,2
]}

Ficai, Denisa ^{[1
]}

Trandafir, Viorica ^{[2
]}

Andronescu, Ecaterina ^{[1
]}

机构：

[1] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Bucharest 011061, Romania

[2] Leather & Footwear Res Inst, Natl Res & Dev Inst Text & Leather INCDTP Div, Collagen Dept, Bucharest 031215, Romania

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2013年 / 1037卷

关键词：

pH influence; Collagen hydrolysate; Scaffold; Bone grafts; Composite material; IN-VITRO; HYDROXYAPATITE; BONE; SCAFFOLDS; NANOCOMPOSITES; STIMULATION; TEMPERATURE; GELATIN; PH;

D O I：

10.1016/j.molstruc.2012.12.052

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

The aim of this study was to study the influence of collagen hydrolysate (HAS) on the formation of ternary collagen-hydrolysate/hydroxyapatite composite materials (COLL-HAS/HA). During the precipitation process of HA, a large amount of brushite is resulted at pH = 7 but, practically pure HA is obtained at pH >= 8. The FTIR data reveal the duplication of the most important collagen absorption bands due to the presence of the collagen hydrolysate. The presence of collagen hydrolysate is beneficial for the management of bone and joint disorders such as osteoarthritis and osteoporosis. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：154 / 159

页数：6

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