MYC - TIMELINE Reflecting on 25 years with MYC

被引：1217

作者：

Meyer, Natalie ^{[2
]}

Penn, Linda Z. ^{[1
]}

机构：

[1] Ontario Canc Inst, Div Canc Genom & Prote, Toronto, ON M5G 2M9, Canada

[2] Amgen Canada Inc, Mississauga, ON L5N 7Y2, Canada

来源：

NATURE REVIEWS CANCER | 2008年 / 8卷 / 12期

关键词：

D O I：

10.1038/nrc2231

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is astonishing how each incremental insight into MYC regulation and function has also had an impact on numerous biological disciplines, including our understanding of molecular oncogenesis in general. Here we chronicle the major advances in our understanding of MYC biology, and peer into the future of MYC research.

引用

页码：976 / 990

页数：15

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