Cellular Level Biocompatibility and Biosafety of ZnO Nanowires

被引：283

作者：

Li, Zhou ^{[1
,2
]}

Yang, Rusen ^{[1
]}

Yu, Min ^{[3
]}

Bai, Fan ^{[1
]}

Li, Cheng ^{[1
]}

Wang, Zhong Lin ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA

[2] Peking Univ, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China

[3] Peking Univ, Dept Biomed Engn, Beijing 100871, Peoples R China

来源：

JOURNAL OF PHYSICAL CHEMISTRY C | 2008年 / 112卷 / 51期

关键词：

D O I：

10.1021/jp808878p

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report the first cellular level study on the biocompatibility and biosafety of ZnO nanowires (NWs). Hela cell line showed a complete biocompatibility to ZnO nanostructures from low to high NW concentrations beyond a couple of production periods. The L929 cell line showed a good reproduction behavior at lower NW concentration, but when the concentration was close to 100 mu g/ml, the viability dropped to similar to 50%. Our study shows the biocompetability and biosafety of ZnO NWs when they are applied in biological applications at normal concentration range.

引用

页码：20114 / 20117

页数：4

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