Microreactor technology and continuous processes in the fine chemical and pharmaceutical industry: Is the revolution underway?

被引:235
作者
Roberge, Dominique M. [1 ]
Zimmermann, Bertin [2 ]
Rainone, Fabio [2 ]
Gottsponer, Michael [2 ]
Eyholzer, Markus [2 ]
Kockmann, Norbert [2 ]
机构
[1] Univ Ottawa, Ottawa, ON K1N 6N5, Canada
[2] Lonza Ltd, CH-3930 Visp, Switzerland
关键词
D O I
10.1021/op8001273
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Microreactors have shown their ability to improve chemical processes and routes; however, their integration into chemical production processes depends not only on technical advances. Cost issues and productions logistics play a crucial role, too, and are highlighted with two different case studies. Economical drivers for the pharmaceutical industry are described with emphasis on future development of microprocess engineering.
引用
收藏
页码:905 / 910
页数:6
相关论文
共 15 条
[11]   Development of an industrial multi-injection microreactor for fast and exothermic reactions - Part II [J].
Roberge, Dominique M. ;
Bieler, Nikolaus ;
Mathier, Meinrad ;
Eyholzer, Markus ;
Zimmermann, Bertin ;
Barthe, Philippe ;
Guermeur, Celine ;
Lobet, Olivier ;
Moreno, Maxime ;
Woehl, Pierre .
CHEMICAL ENGINEERING & TECHNOLOGY, 2008, 31 (08) :1155-1161
[12]  
STANGE O, 2008, TOPICAL C P AM I CHE
[13]   Harnessing microreactions [J].
Thayer, AM .
CHEMICAL & ENGINEERING NEWS, 2005, 83 (22) :43-+
[14]  
WARMINGTON A, 2008, SPECIALTY CHEM MAGAZ, P40
[15]   Process chemistry: The science, business, logic, and logistics [J].
Zhang, Tony Y. .
CHEMICAL REVIEWS, 2006, 106 (07) :2583-2595