Hypertriglyceridemia as a possible risk factor for prostate cancer

被引：59

作者：

Wuermli, L

Joerger, M

Henz, S

Schmid, HP

Riesen, WF

Thomas, G

Krek, W

Cerny, T

Gillessen, S

机构：

[1] Kantonsspital, Dept Internal Med, CH-9007 St Gallen, Switzerland

[2] Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Expt Therapy, Amsterdam, Netherlands

[3] Kantonsspital, Dept Urol, CH-9007 St Gallen, Switzerland

[4] Kantonsspital, Dept Clin Chem & Hematol, CH-9007 St Gallen, Switzerland

[5] Univ Cincinnati, Genome Res Inst, Cincinnati, OH 45221 USA

[6] ETH Honggerberg, Inst Cell Biol, CH-8093 Zurich, Switzerland

[7] Kantonsspital, Dept Med Oncol, CH-9007 St Gallen, Switzerland

来源：

PROSTATE CANCER AND PROSTATIC DISEASES | 2005年 / 8卷 / 04期

关键词：

hyperlipidemia; serum cholesterol; serum triglycerides;

D O I：

10.1038/sj.pcan.4500834

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We retrospectively studied anthropometric and laboratory parameters ( including serum triglycerides, cholesterol), as well as comedication in 504 patients diagnosed with prostate cancer between January 1997 and August 2002 at a single referral center, and compared these patients with 565 age-matched patients with benign prostatic hyperplasia. A positive correlation was found between serum triglycerides and prostate cancer ( odds ratio: 1.148/ mmol/ l; 95% confidence interval (CI) 1.003 - 1.315; P<0.05) after correcting for age, body mass index, diabetes and comedication with statins. Hypertriglyceridemia may increase the risk of prostate cancer, and the prognostic relevancy of serum triglycerides should be studied prospectively.

引用

页码：316 / 320

页数：5

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