Small for gestational age infant in association with maternal prothrombin gene variant (nt 20210A)

被引：12

作者：

Verspyck, E ^{[1
]}

Le Cam-Duchez, V

Gravier, A

Descargues, G

Marpeau, L

Borg, JY

机构：

[1] Rouen Univ Hosp, Dept Obstet & Gynecol, Rouen, France

[2] Rouen Univ Hosp, Dept Haematol & Coagulat Disorders, Rouen, France

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1999年 / 83卷 / 02期

关键词：

intrauterine growth retardation; placental thrombosis; thrombophilic disorders; prothrombin gene variant;

D O I：

10.1016/S0301-2115(98)00330-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Most of disproportionate infants born small for gestational age (SGA) have an history of placental dysfunction with no explained cause. We report a case of an unexplained SGA infant with placental infarctions and thrombosis. Maternal thrombophilic disorder tests revealed that the patient was heterozygous for the A20210 prothrombin gene variant a newly identified thrombotic risk factor. It may be suggest that prothrombin gene variant, as factor V Leiden, could be a genetic risk factor for placental insufficiency. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：143 / 144

页数：2