The spread of carbapenem-resistant Enterobacteriaceae in South Africa: Risk factors for acquisition and prevention

被引：35

作者：

Brink, Adrian ^{[1
]}

Coetzee, Jennifer ^{[2
]}

Clay, Cornelis ^{[2
]}

Corcoran, Craig ^{[2
]}

van Greune, Johan ^{[4
]}

Deetlefs, J. D. ^{[4
]}

Nutt, Louise ^{[3
]}

Feldman, Charles ^{[5
,6
,7
]}

Richards, Guy ^{[5
,6
,7
]}

Nordmann, Patrice ^{[8
,9
]}

Poirel, Laurent ^{[8
,9
]}

机构：

[1] Milpk Hosp, Dept Clin Microbiol, Ampath Natl Lab Serv, Johannesburg, South Africa

[2] Natl Reference Lab, Dept Clin Microbiol & Mol Biol, Ampath Natl Lab Serv, Centurion, Gauteng, South Africa

[3] Ampath Natl Lab Serv, Port Elizabeth, South Africa

[4] Ampath Natl Lab Serv, Cape Town, South Africa

[5] Charlotte Maxeke Johannesburg Acad Hosp, Dept Crit Care, Johannesburg, South Africa

[6] Charlotte Maxeke Johannesburg Acad Hosp, Div Pulrnonol, Johannesburg, South Africa

[7] Univ Witwatersrand, Johannesburg, South Africa

[8] Hosp Bicetre, Assistance Publ Hop Paris, Serv Bacteriol Virol, Fac Med, K Bicetre, France

[9] Univ Paris 11, K Bicetre, France

来源：

SAMJ SOUTH AFRICAN MEDICAL JOURNAL | 2012年 / 102卷 / 07期

关键词：

KLEBSIELLA-PNEUMONIAE; EMERGENCE; EPIDEMIOLOGY; COLISTIN; KPC-2;

D O I：

10.7196/SAMJ.5789

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

New, effective antibiotics are only likely to become available in 15 - 20 years. To prevent deaths from untreatable Gram-negative infections in South Africa, the rights of any doctor, whether in general or in hospital practice, to indiscriminately prescribe whatever antibiotic they wish, and in whatever fashion, must be challenged. Furthermore, although prevention of the emergence and subsequent spread of carbapenem-resistant Enterobacteriaceae (CRE) has focused on acute and chronic care facilities and inter alia on antibiotic exposure in these institutions, CRE may soon become an issue within entire communities, highlighting a role for public health authorities in CRE prevention efforts.

引用

页码：599 / 601

页数：3

共 14 条

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