Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates

被引:75
作者
Oster, P
Zanchi, A
Cresti, S
Lattanzi, M
Montagnani, F
Cellesi, C
Rossolini, GM
机构
[1] Univ Siena, Sez Microbiol, Dipartimento Biol Mol, I-53100 Siena, Italy
[2] Univ Siena, Ist Clin Malattie Infettive, I-53100 Siena, Italy
关键词
D O I
10.1128/AAC.43.10.2510
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Erythromycin resistance rates were found to be increased, from 7.1 in 1993 to 32.8% in 1997, among community-acquired Streptococcus pneumoniae isolates from the Siena area of central Italy. Most of the erythromycin-resistant isolates carried ermAM determinants and were also resistant to josamycin and clindamycin, whereas a minority (5.8%) carried mefA determinants and remained susceptible to the latter drugs.
引用
收藏
页码:2510 / 2512
页数:3
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