Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates

被引：75

作者：

Oster, P

Zanchi, A

Cresti, S

Lattanzi, M

Montagnani, F

Cellesi, C

Rossolini, GM

机构：

[1] Univ Siena, Sez Microbiol, Dipartimento Biol Mol, I-53100 Siena, Italy

[2] Univ Siena, Ist Clin Malattie Infettive, I-53100 Siena, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 10期

关键词：

D O I：

10.1128/AAC.43.10.2510

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Erythromycin resistance rates were found to be increased, from 7.1 in 1993 to 32.8% in 1997, among community-acquired Streptococcus pneumoniae isolates from the Siena area of central Italy. Most of the erythromycin-resistant isolates carried ermAM determinants and were also resistant to josamycin and clindamycin, whereas a minority (5.8%) carried mefA determinants and remained susceptible to the latter drugs.

引用

页码：2510 / 2512

页数：3