Sigpep: Calculating unique peptide signature transition sets in a complete proteome background

被引：6

作者：

Helsens, Kenny ^{[1
,2
]}

Mueller, Michael ^{[3
]}

Hulstaert, Niels ^{[1
,2
]}

Martens, Lennart ^{[1
,2
]}

机构：

[1] VIB, Dept Med Prot Res, B-9000 Ghent, Belgium

[2] Univ Ghent, Dept Biochem, B-9000 Ghent, Belgium

[3] Wellcome Trust Genome Campus, European Bioinformat Inst, EMBL Outstn, Cambridge, England

来源：

PROTEOMICS | 2012年 / 12卷 / 08期

关键词：

Bioinformatics; Mass spectrometry; Selected reaction monitoring; Standards; TARGETED PROTEOMICS; MASS-SPECTROMETRY; PLASMA-PROTEINS; ASSAYS; SELECTION; DATABASE; SYSTEM; IONS;

D O I：

10.1002/pmic.201100566

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have created a new software platform called sigpep that analyzes transition redundancy in selected reaction monitoring assays. Building on this platform, we also created a web application to generate transition sets with unique signatures for targeted peptides. The platform has been made available under the permissive Apache 2.0 open-source license, and the web application can be accessed from .

引用

页码：1142 / 1146

页数：5

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