Microbial 7-OH epimerisation of bile acids

被引:11
作者
Dean, M [1 ]
Fantin, G [1 ]
Fogagnolo, M [1 ]
Medici, A [1 ]
Pedrini, P [1 ]
Poli, S [1 ]
机构
[1] Univ Ferrara, Dipartimento Chim, I-44100 Ferrara, Italy
关键词
D O I
10.1246/cl.1999.693
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The microbial 7-OH epimerisation of cholic and chenodeoxycholic acids with Xanthomonas maltophilia CBS 827.97 to ursocholic and ursodeoxycholic acids with scarsity of oxygen is described. With normal pressure of oxygen the 7-ketocholic and the 7-ketochenodeoxycholic acids are obtained. No biotransformation is achieved in anaerobic conditions.
引用
收藏
页码:693 / 694
页数:2
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