Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia

被引：72

作者：

Liao, Yuxiao ^{[1
,2
]}

Peng, Zhao ^{[1
,2
]}

Chen, Liangkai ^{[1
,2
]}

Zhang, Yan ^{[1
,2
]}

Cheng, Qian ^{[1
,2
]}

Nussler, Andreas K. ^{[3
]}

Bao, Wei ^{[4
]}

Liu, Liegang ^{[1
,2
]}

Yang, Wei ^{[1
,2
]}

机构：

[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Food Nutr & Safety, Dept Nutr & Food Hyg, Wuhan, Hubei, Peoples R China

[2] Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, MOE Key Lab Environm & Hlth, Wuhan, Hubei, Peoples R China

[3] Univ Tubingen, Dept Traumatol, BG Trauma Ctr, Tubingen, Germany

[4] Univ Iowa, Coll Publ Hlth, Dept Epidemiol, Iowa City, IA 52242 USA

来源：

AGING AND DISEASE | 2019年 / 10卷 / 01期

基金：

中国国家自然科学基金;

关键词：

age-related sarcopenia; whey protein; resistance training; sex hormones; gender differences; gut microbiota; SKELETAL-MUSCLE MASS; LEUCINE-ENRICHED WHEY; ESSENTIAL AMINO-ACIDS; HAND GRIP STRENGTH; QUALITY-OF-LIFE; FAT-FREE MASS; GUT MICROBIOTA; TRANSLATIONAL CONTROL; DIETARY-PROTEIN; OLDER-ADULTS;

D O I：

10.14336/AD.2018.0325

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

030301 [社会学]; 100201 [内科学];

摘要：

Skeletal muscle aging is characterized by decline in skeletal muscle mass and function along with growing age, which consequently leads to age-related sarcopenia, if without any preventive timely treatment. Moreover, age-related sarcopenia in elder people would contribute to falls and fractures, disability, poor quality of life, increased use of hospital services and even mortality. Whey protein (WP) and/or resistance training (RT) has shown promise in preventing and treating age-related sarcopenia. It seems that sex hormones could be potential contributors for gender differences in skeletal muscle and age-related sarcopenia. In addition, skeletal muscle and the development of sarcopenia are influenced by gut microbiota, which in turn is affected by WP or RT. Gut microbiota may be a key factor for WP and/or RT against age-related sarcopenia. Therefore, focusing on sex hormones and gut microbiota may do great help for preventing, treating and better understanding age-related sarcopenia.

引用

页码：157 / 173

页数：17

共 172 条

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