Zinc-mediated radical reactions of per- (or poly)fluorophenyl aromatic aldimines in aqueous media

被引：17

作者：

Liu, XY

Zhu, SZ

Wang, SW

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[2] Anhui Normal Univ, Sch Chem & Mat Sci, Inst Organ Chem, Wuhu 241000, Anhui, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2004年 / 05期

关键词：

polyfluororinated amines; imines; zinc; alkyl halides; radical reactions;

D O I：

10.1055/s-2004-816004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The intermolecular additions of alkyl halides to per- (or poly)fluorophenyl aromatic aldimines using zinc as a single-electron-transfer radical initiator have been studied in aqueous media. The reaction proceeds well for imines with different substituents at room temperature under air atmosphere and the corresponding fluorine-containing amines and 1,2-diamines are obtained in poor to,Good yields. A tentative reaction mechanism is proposed.

引用

页码：683 / 691

页数：9

共 51 条

[1]

AMBROSIO MD, 1996, HELV CHIM ACTA, V79, P51

[2]

Banks R.E., 1994, ORGANOFLUORINE CHEM

[3] ENANTIOSELECTIVE SYNTHESIS OF HOMOALLYLIC AMINES BY ADDITION OF ALLYLMETAL REAGENTS TO IMINES DERIVED FROM (S)-VALINE ESTERS [J].